Nature's Way Evening Primrose Oil 1300mg
A versatile, budget-friendly menopause support supplement that shines for skin dryness and breast tenderness, with modest benefits for hot flashes.
- Cold-pressed extraction preserves GLA integrity
- Non-GMO verified with a clean formula
- Versatile benefits — hot flashes, skin health, breast tenderness
- Very affordable at around $15 per month
- Hot flash evidence is mixed — works better for mild symptoms
- Large softgel may be difficult for some to swallow
- May interact with blood-thinning medications
Nature’s Way Evening Primrose Oil 1300mg is a cold-pressed, Non-GMO source of gamma-linolenic acid (GLA) — an omega-6 fatty acid that may support women through menopause on multiple fronts. From hot flashes and breast tenderness to the dry, thinning skin that often accompanies declining estrogen levels, evening primrose oil offers versatile benefits at a remarkably affordable price. If you’re looking for a single supplement that addresses several menopausal concerns at once, this is a smart place to start.
What Is Nature’s Way Evening Primrose Oil?
Nature’s Way is one of America’s oldest and most established supplement brands, founded in 1969. Their Evening Primrose Oil uses cold-pressed extraction — a method that avoids the high heat and chemical solvents that can damage the delicate GLA content. This matters because GLA is what makes evening primrose oil useful, and how the oil is extracted directly affects how much active GLA survives the process.
Evening primrose (Oenothera biennis) is a flowering plant native to North America. Its seeds contain one of the richest natural sources of GLA, an omega-6 fatty acid that your body uses to produce anti-inflammatory prostaglandins. These compounds play a role in hormone regulation, skin health, and inflammatory responses — all areas that become more relevant during menopause.
What’s Inside
Each 1300mg softgel provides the full spectrum of evening primrose oil fatty acids, with approximately 117mg of GLA and 910mg of linoleic acid per softgel. The oil is cold-pressed from Non-GMO evening primrose seeds.
The softgel shell is made from gelatin, glycerin, and water. There are no artificial colors, flavors, or preservatives. The formula is free from gluten, soy, dairy, and yeast. Nature’s Way uses TRU-ID genetic testing to verify the botanical identity of the evening primrose used.
What the Research Says
GLA has been studied for several menopause-related concerns. A 2013 randomized controlled trial published in the Archives of Gynecology and Obstetrics found that women taking evening primrose oil experienced significant reductions in the frequency, severity, and duration of hot flashes compared to placebo over 6 weeks. The authors noted that evening primrose oil may work by modulating prostaglandin synthesis, which influences thermoregulation.
For skin health, GLA’s benefits are well-documented. A study published in the International Journal of Cosmetic Science found that GLA supplementation improved skin moisture, elasticity, and firmness. A separate review in the Journal of Lipid Research confirmed that GLA supplementation increases GLA levels in skin tissue and supports the skin’s barrier function — particularly relevant for women experiencing the skin changes that accompany declining estrogen.
For breast tenderness, a meta-analysis of clinical trials found that evening primrose oil provided modest but meaningful relief for cyclical breast pain. While this is more relevant for perimenopausal women still experiencing cycles, it remains one of the more commonly reported benefits.
Who Is This Best For?
Nature’s Way Evening Primrose Oil is a particularly good fit if you:
- Experience dry or thinning skin — GLA directly supports the skin’s moisture barrier, and this is one of the best-evidenced benefits
- Have mild to moderate hot flashes — evening primrose oil may help, though women with severe symptoms may need a more targeted approach
- Deal with breast tenderness — particularly during perimenopause when cyclical pain is still occurring
- Want a multi-purpose supplement — rather than buying separate products for skin, hot flashes, and breast comfort, one supplement covers all three
- Are budget-conscious — at around $15 per month, this is one of the most affordable menopause support options
If your primary concern is hot flashes and you want the strongest evidence, Remifemin Black Cohosh has more robust clinical data specifically for that symptom.
How to Take It
Take one softgel daily with food. Some women take two softgels daily for more noticeable effects — this is within the dosage range used in clinical studies. Taking it with a meal that contains some fat improves absorption of the oil-based GLA.
Timing tip: If you take two softgels, split the dose — one with breakfast and one with dinner — for more even GLA levels throughout the day.
Interactions to watch: Evening primrose oil has mild blood-thinning properties. If you take warfarin, aspirin, clopidogrel, or other anticoagulants, discuss evening primrose oil with your doctor before starting. Discontinue use at least two weeks before any planned surgery.
Always consult your doctor before starting evening primrose oil, particularly if you take blood-thinning medications or have a bleeding disorder.
The Bottom Line
Nature’s Way Evening Primrose Oil 1300mg is the kind of supplement that earns its spot through sheer versatility. While it may not be the most powerful option for any single menopausal symptom, it offers meaningful support across several common concerns — skin dryness, hot flashes, and breast tenderness — all from one affordable softgel. For women over 50 who want a gentle, multi-benefit addition to their daily routine, this is a reliable and well-priced starting point.
Frequently Asked Questions
Does evening primrose oil really help with hot flashes?
The evidence is mixed but encouraging. A 2013 clinical trial published in the Archives of Gynecology and Obstetrics found that women taking evening primrose oil experienced reduced frequency, severity, and duration of hot flashes compared to placebo over 6 weeks. However, not all studies have been positive. Evening primrose oil may work better for mild to moderate symptoms rather than severe hot flashes. Many women find it most helpful as part of a broader approach.
How much GLA is in each Nature's Way Evening Primrose Oil softgel?
Each 1300mg softgel provides approximately 117mg of GLA (gamma-linolenic acid), along with other beneficial fatty acids including linoleic acid. The GLA content comes from cold-pressed evening primrose oil, which naturally contains about 9-10% GLA. One to two softgels daily is the standard recommended dose.
Can evening primrose oil help with dry skin during menopause?
Yes — this is actually one of the better-supported benefits. GLA plays a key role in maintaining the skin's moisture barrier. As estrogen levels decline during menopause, skin tends to become drier and thinner. A study in the International Journal of Cosmetic Science found that evening primrose oil supplementation improved skin moisture, elasticity, and firmness over 12 weeks. Many women take it specifically for this benefit.
Are there any side effects or drug interactions with evening primrose oil?
Evening primrose oil is generally well tolerated, with occasional mild stomach upset or headache. The most important interaction is with blood-thinning medications — GLA has mild antiplatelet effects and could theoretically increase bleeding risk when combined with warfarin, aspirin, or other blood thinners. Stop taking evening primrose oil at least two weeks before any scheduled surgery. Always discuss it with your doctor if you take blood thinners.